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What will the lifetime be. Patient Performance Status Adequate patient performance status is an important prerequisite for hepatic resections of any type and can be quantified using the Karnofsky Performance Score 10 Index 487 Cyclin-dependent kinases (CDKs), astrocytoma expression, 345 cell cycle regulation, 344, 345 small molecule inhibitors, 345 Cytokine gene therapy, see Gene therapy; Interferon-γ; Interleukin-2 D Deep vein thrombosis, see Venous thromboembolism Depression, nursing management, 290 Dexamethasone, see Steroids Diazepam, photodynamic therapy combination, 468 Diffuse pontine glioma, children, clinical features, 51, 52, 58, 59 treatment, 52, 53 computed tomography findings, 97 Diffusion tensor imaging, see Magnetic resonance imaging DNA repair, radiobiology, 248 Epithelioid variant, glioblastoma, 7, 11 Erlotinib, epidermal growth factor receptor inhibition, 340 F Farnesyltransferase inhibitors, Ras inhibition, 344 Fas, apoptosis induction, 406 Fatigue, definition, 207 nursing management, 290, 291 treatment, 207, 208 underdiagnosis, 207 Fertility, concerns, 287, 288 Fibronectin, antibody targeting, 384 Flavopyridol, cyclin-dependent kinase inhibition, 345 Fluorodeoxyglucose, see Positron emission tomography Foscan, photodynamic therapy, 464 G Gamma Knife, see Stereotactic radiosurgery Gangliosides, antibody targeting, 384, 385 GBM, see Glioblastoma multiforme Gefitinib, epidermal growth factor receptor inhibition, 340 Gemistocytic astrocytoma, features, 5, 6, 8 Gene expression, positron emission tomography studies, 155 Gene therapy, see also Interferon-γ; Interleukin-2 barriers, 419, 420 historical perspective, 419 oncolytic virus delivery, 397400 prospects, 428 viral vectors, adenovirus, 422424 herpes simplex virus-1, 424426 immunomodulatory gene delivery, 425427 Newcastle disease virus, 425 reovirus, 425 retrovirus, 420, 422 vaccinia virus, 426, 427 GFAP, see Glial fibrillary acidic protein GFP, see Green fluorescent protein Giant cell variant, glioblastoma, 8, 13 Gleevec, see Imatinib mesylate Glial fibrillary acidic protein (GFAP), histological grading, 68, 14 GliaSite® RTS, brachytherapy, 253, 254 Glioblastoma multiforme (GBM), Donepezil, fatigue management in brain tumor patients, 208 Dorsal exophytic brainstem tumors, children, 53, 54 Driving, seizure free interval, 200202 E EGFR, see Epidermal growth factor receptor Ependymoma, computed tomography findings, 97 grading, 15, 16, 2730 Epidemiology, high-grade glioma, age distribution, 60 ethnic distribution, 60 genetic syndromes, 60, 61 geographic distribution, 60 incidence, 59, 60 radiofrequency exposure studies, 61, 62 sex distribution, 60 tumor types, 59 viral induction, 61 Epidermal growth factor receptor (EGFR), antibody targeting, 338, 376, 383 glioma expression, 339, hot forex multi terminal inhibitors, antibodies, 338, 376, 383 radiosensitization, 237, 238 resistance, 277 small molecule inhibitor types and mechanisms, 340 systemic chemotherapy for intracerebral tumors.
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