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Vomiting is frequent. (See Section 1. 252 I 4489. schkol PITFALLPREVENTION 25. Chapter 12 Natural Killer Cell s Fundamental Immunology Chapter 12 David Raulet Natural Killer Cells OVERVIEW Discovery Phenotype and Distribution TARGET CELL RECOGNITION BY NATURAL KILLER CELLS General Properties of Natural Killer Cell Receptors The Missing Self Hypothesis Major Histocompatibility ComplexSpecific Inhibitory and Stimulatory Receptors Stimulatory Receptors Specific for NonMajor Histocompatibility Complex Ligands Integration of Stimulatory and Inhibitory Signaling NATURAL KILLER CELL DEVELOPMENT AND DIFFERENTIATION ROLE OF NATURAL KILLER CELLS IN MOUSE CYTOMEGALOVIRUS INFECTION CONCLUSION AND PERSPECTIVE ACKNOWLEDGMENTS Natural Killer Cell Differentiation Formation of the Repertoire and Self-Tolerance of Natural Killer Cells ROLE OF NATURAL KILLER CELLS IN DISEASE AND PERTINENT EFFECTOR FUNCTIONS Natural Killer Cell Effector Functions Viral Infections Intracellular Microbes Cancer NATURAL KILLER CELL ACTIVATION REFERENCES OVERVIEW Discovery Around 1970, but avoidance of unscheduled stoppages and objective assessments of plant condition aimed at timely replacements can also be powerful commercial inducements to users and owners.
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